• cardiovascular mortality

    From ScienceDaily@1:317/3 to All on Tuesday, March 15, 2022 22:30:44
    cardiovascular mortality
    Research also discovers potentially worsening disparities in the U.S.


    Date:
    March 15, 2022
    Source:
    University Hospitals Cleveland Medical Center
    Summary:
    A new study found people living in socially-deprived areas of the
    United States are more likely to die prematurely from cardiovascular
    complications.



    FULL STORY ========================================================================== People living in socially-deprived areas of the United Statesare more
    likely to die prematurely from cardiovascular (CV) complications according
    to new research published recently in Mayo Clinic Proceedings.The study, completed by researchers at University Hospitals (UH) Harrington Heart & Vascular Institute, found social deprivation can explain a significant proportion of the geographic variation in premature cardiovascular
    mortality in the U.S.


    ========================================================================== Socioeconomic deprivation is defined by a number of social and economic
    factors including education, income, employment and neighborhood
    environment. A large gap exists in explaining premature CV deaths
    across the U.S. which cannot be totally attributed to traditional risk
    factors such as high cholesterol. Recent evidence suggests socioeconomic deprivation is a risk factor for this type of mortality.

    "Socioeconomic status plays a big role in access to preventive care,
    risk factor control, and incidence of disease," said Sadeer Al-Kindi,
    MD, cardiologist and co-director of the Center for Integrated and Novel Approaches in Vascular-Metabolic Disease (CINEMA) with UH Harrington
    Heart & Vascular Institute and the study's senior author. "UH is
    committed to improving the health of all people by advancing science
    and human health. A large part of that is discovering the root cause
    of disease. With this study, we wanted to determine whether premature cardiovascular mortality is associated with socioeconomic deprivation
    and how premature cardiovascular mortality changed over time by social deprivation." In "Socioeconomic Deprivation and Premature Cardiovascular Mortality in the United States" researchers completed a cross-sectional analysis of United States county-level death certificate data from 1999
    to 2018 using files maintained by the U.S. National Center for Health
    and Statistics. They looked at people from the ages of 25 to 64 who died
    from cardiovascular conditions.

    They used linear regression analysis to document two integrated metrics
    of socioeconomic deprivation: Social Deprivation Index (SDI) and county
    Area Deprivation Index (ADI).

    Results from this research showed that counties with high social
    deprivation had the highest rates of premature cardiovascular
    deaths. Additionally, from 1999 to 2018 premature cardiovascular mortality decreased to a lesser extent in socially deprived counties compared with affluent counties. In fact, indicators of social deprivation directly
    explained a significant proportion of the geographic differences in
    premature CV mortality in the U.S.

    "Health and structural inequities in poor communities have been ignored
    for too long. We now know that where you live, inequities and other
    components embedded in the environment are powerful determinants of
    mortality, often from chronic non-communicable disease. Most importantly, shedding light on this pervasive issue compels us to act upon the
    information," said Sanjay Rajagopalan, MD, Chief of Cardiovascular
    Medicine and Chief Academic and Scientific Officer of UH Harrington
    Heart & Vascular Institute and co-author of the study, as well as the
    Herman K. Hellerstein, MD, Chair in Cardiovascular Research.

    UH is taking action in a multitude of ways, including through its work in
    the community thanks to the ACHIEVE GreatER initiative. A "transformative" $18.2 million federal grant from the National Institutes of Health's P50 program will facilitate medical and cardiovascular care provided directly
    to people living in Cuyahoga Metropolitan Housing Authority, one of
    the nation's largest and oldest subsidized housing programs. Additional
    efforts by the study team are focused on understanding the integrated
    social and environmental underpinnings of premature cardiovascular
    disease in Northeast Ohio and nationally.

    "Regardless of where they live or how much money they make, all people
    should have the opportunity to receive the necessary medical resources
    and support to have a healthier life," said Dr. Mehdi Shishehbor, DO,
    MPH, PhD, President of UH Harrington Heart & Vascular Institute, and
    the Angela and James Hambrick Chair in Innovation.

    Prior studies have explored the relationship between race and premature
    CV mortality or individual socioeconomic factors (income, high school education) and CV mortality.

    "To our knowledge, this is the first study to demonstrate a longitudinal association between multiple integrated metrics of socioeconomic
    deprivation and premature cardiovascular mortality adjusted for
    traditional cardiovascular risk factors, while also showing potentially worsening disparities," said Dr.

    Al-Kindi.


    ========================================================================== Story Source: Materials provided by University_Hospitals_Cleveland_Medical_Center. Note: Content may be
    edited for style and length.


    ========================================================================== Journal Reference:
    1. Graham H. Bevan, Khurram Nasir, Sanjay Rajagopalan, Sadeer Al-Kindi.

    Socioeconomic Deprivation and Premature Cardiovascular Mortality
    in the United States. Mayo Clinic Proceedings, 2022; DOI: 10.1016/
    j.mayocp.2022.01.018 ==========================================================================

    Link to news story: https://www.sciencedaily.com/releases/2022/03/220315141751.htm

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