People with diabetes and cognitive decline may be at higher risk for
heart disease
Date:
April 21, 2022
Source:
The Endocrine Society
Summary:
People with type 2 diabetes who have cognitive impairment could
be at greater risk for stroke, heart attack or death than other
individuals with diabetes, according to a new study.
FULL STORY ========================================================================== People with type 2 diabetes who have cognitive impairment could be at
greater risk for stroke, heart attack or death than other individuals
with diabetes, according to a new study published in the Endocrine
Society's Journal of Clinical Endocrinology and Metabolism.
========================================================================== Cognitive impairment is when a person has trouble remembering, learning
new things, concentrating or making decisions that affect their everyday
life. More than 16 million people in the United States are living with cognitive impairment, and age is the biggest risk factor. Cognitive
impairment ranges from mild to severe and has been associated with
Alzheimer's disease, heart disease, stroke and diabetes.
"Our study found low scores on cognitive tests predicted heart disease
in people with diabetes and other heart risk factors," said co-author
Hertzel C.
Gerstein, M.D., of McMaster University in Hamilton, Canada. "Although the explanation for this remains unclear, proven heart medications should
be offered to these patients to reduce their future risk of a heart
attack or stroke." The researchers assessed the relationship between
cognitive function and future cardiovascular events in 8,772 people
with type 2 diabetes from the REWIND trial during more than five years
of follow up. They found that people with the lowest level of cognitive function had a higher risk of heart attack and stroke than those with
higher levels of cognitive function.
People with severe cognitive impairment were up to 1.6 times more likely
to experience major adverse cardiovascular events, and 1.8 times more
likely to experience a stroke or die compared to people without cognitive impairment.
These findings suggest cognitive function could predict a person's future
risk of heart disease.
The study received funding from Eli Lilly and Company.
========================================================================== Story Source: Materials provided by The_Endocrine_Society. Note: Content
may be edited for style and length.
========================================================================== Journal Reference:
1. Tali Cukierman-Yaffe, Hertzel C Gerstein, Jan Basile, M Angelyn
Bethel,
Ernesto G Cardona-Mun~oz, Ignacio Conget, Gilles Dagenais, Edward
Franek, Stephanie Hall, Nicolae Hancu, Petr Jansky, Mark Lakshmanan,
Fernando Lanas, Lawrence A Leiter, Patricio Lopez-Jaramillo, Valdis
Pirags, Nana Pogosova, Jeffrey Probstfield, Purnima Rao-Melacini,
Chinthanie Ramasundarahettige, Peter J Raubenheimer, Matthew C
Riddle, Lars Ryde'n, Jonathan E Shaw, Wayne H-H Sheu, Theodora
Temelkova-Kurktschiev. Novel Indices of Cognitive Impairment
and Incident Cardiovascular Outcomes in the REWIND Trial. The
Journal of Clinical Endocrinology & Metabolism, 2022; DOI:
10.1210/clinem/dgac200 ==========================================================================
Link to news story:
https://www.sciencedaily.com/releases/2022/04/220421094041.htm
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